tag:blogger.com,1999:blog-7120134997435393696.post7002048279973053368..comments2023-11-13T08:20:20.587-08:00Comments on Magnus Ducatus Lituaniae Project: Last posting in the year 2011Project "Magnus Ducatus Lituaniae"http://www.blogger.com/profile/06764361071403376842noreply@blogger.comBlogger5125tag:blogger.com,1999:blog-7120134997435393696.post-46417658762175200092014-01-22T21:03:55.873-08:002014-01-22T21:03:55.873-08:00I have a bacterial SNP haplotype data for 200 samp...I have a bacterial SNP haplotype data for 200 samples (1000 SNP positions). How do I define donor and recipient for this data? I would appreciate if somebody could guide me on how to format my dataset for input into chromopainter. I want to run in a all-against-all mode.Anonymoushttps://www.blogger.com/profile/09187772145928705329noreply@blogger.comtag:blogger.com,1999:blog-7120134997435393696.post-25580230564707129582012-01-08T10:36:13.740-08:002012-01-08T10:36:13.740-08:00"When we adjusted the data for the locus on c..."When we adjusted the data for the locus on chromosome 15q and performed a new genomescan<br />(data not shown), the next largest test statistics were LODs of 1.7 and 1.5, on chromosomes 12 and<br />11, respectively, which were slightly higher LOD scores than seen in the scan unadjusted for the 15q<br />locus. Although these were not significant at the genome-wide level, the chromosome 11 peak is<br />interesting as it is in a region that contains the tyrosinase gene (TYR, aka OCA1A on 11q14-11q21)<br />which plays a role in melanine formation in the eye (Frudakis et al., 2003; Oetting and King, 1993)."<br />http://genepi.qimr.edu.au/contents/p/staff/CV450.pdfProject "Magnus Ducatus Lituaniae"https://www.blogger.com/profile/06764361071403376842noreply@blogger.comtag:blogger.com,1999:blog-7120134997435393696.post-47127034616969559742012-01-08T10:30:45.659-08:002012-01-08T10:30:45.659-08:00I think that high numbers of IBD segments are expl...I think that high numbers of IBD segments are explained by "the increase in IBD sharing on chromosome 11q13 (lod=1.9) that seemed to be supported by parametric analysis, because D11S4076, located in this region, gave a lod of 1.55 under a dominant transmission A cautious interpretation of these signals is warranted, because several methods of analysis under two phenotype models were employed; therefore, signals could have arisen from random statistical fluctuations." (A high-density genome scan detects evidence for a bipolar-disorder susceptibility locus on 13q32 and other potential loci on 1q32 and 18p11.2)<br />http://www.pnas.org/content/96/10/5604.full.pdfProject "Magnus Ducatus Lituaniae"https://www.blogger.com/profile/06764361071403376842noreply@blogger.comtag:blogger.com,1999:blog-7120134997435393696.post-28557143894866694332012-01-08T10:19:56.144-08:002012-01-08T10:19:56.144-08:00Thetick,
Thank you for reporting a trouble with C...Thetick,<br /><br />Thank you for reporting a trouble with Chr 9 link.<br />I have fixed it.Project "Magnus Ducatus Lituaniae"https://www.blogger.com/profile/06764361071403376842noreply@blogger.comtag:blogger.com,1999:blog-7120134997435393696.post-42743840205722842572012-01-07T22:41:46.713-08:002012-01-07T22:41:46.713-08:00Why are the numbers of IBD segments so high for ch...Why are the numbers of IBD segments so high for chromosome 11 orders of magnitude than others? Also the link above for chromosome 9 takes me the chromosome 20 file.thetickhttps://www.blogger.com/profile/17829092593676897606noreply@blogger.com